ramen and pickles

science, technology, and medicine served up with some tasty noodles

Structure of DNA from an X-ray Diffraction Pattern

I don’t remember learning exactly how Watson & Crick got to the double helix structure from Rosalind Franklin’s diffraction pattern (Photo 51).

Dna

However, J Michael McBride gives a great overview of X-ray diffraction in his organic chemistry lectures and explains how you can read the offset double helix structure and get the helix spacing right from the image.

http://academicearth.org/lectures/x-ray-diffraction

http://academicearth.org/lectures/electron-difference-density-revealing-bonds

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